WRAIR GOCO Red Blood Cell Storage Lab
Abstract
The Bionetics Corporation staffed and maintained facilities to manufacture a hemoglobin based blood substitute and to support red blood cell preservation and pathogen inactivation research for the Blood Research Detachment and Department, Walter Reed Army Institute of Research, at 1413 Research Boulevard, Rockville MD 20850 and later at Building 503, Walter Reed Forest Glen Annex, Silver Spring, MD 20910. During the operation of the hemoglobin production facility, 106.04 L of hemoglobin solution containing 11.32 kg of hemoglobin was manufactured, which met or exceeded contract specifications. Three specialty products were produced and the facility was prepared for indefinite shut down. Contract staff completed a series of in vitro experiments and clinical trials, which led to the development of red cell preservation systems extending the shelf life of refrigerated blood from 6 to 12 weeks and a US patent. Data from the laboratory resulted in the publication of 12 manuscripts and six abstracts in the peer- reviewed literature. Evaluation of two pathogen-inactivation technologies for eradication of infectious agents in blood products are in progress. The work done under this contract by the Bionetics Corporation helped advanced the WRAIR Blood Research mission.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2002
- Accession Number
- ADA408119
Entities
People
- Lloyd E. Lippert