Molecular Epidemiology of Ovarian Cancer
Abstract
The aim of this Program is to study the association between epidemiologic risk factors, low-risk genes, and histologic and novel molecular subtypes of ovarian cancer. Funding for the study began in September 2001 and we have since established systems for case ascertainment and recruitment at each of the collaborating sites. Data-collection instruments have been finalized and piloted (using local pilot funding) at the Royal Women's Hospital, Brisbane and at the Mater and Wesley Hospitals and 90% of eligible cases (82 patients) have consented to participate and completed the questionnaires. Project managers for the epidemiology and biospecimen cores have been appointed. A tracking database has been established and the biospecimen database substantially upgraded. SNP detection methodologies have been established. Our major task has been obtain IRC approval at 14 participating sites (complete except for one site), and subsequently obtaining HSRRB approval. Given the Australian context, some of the IRC's have not had an USA FWA in place. This has necessitated obtaining SPA at such sites. All centers in South Australia and NSW have both FWA and IRC approval, and we believe that the study will commence very soon in those states, pending final HSRRB approval.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2002
- Accession Number
- ADA409447
Entities
People
- Adele Green
- Anna deFazio
- David Bowtell
- Dorota Gertig
- Georgia Chenevix-Trench
Organizations
- Peter MacCallum Cancer Centre