Natural History of Breast Density and Breast Cancer Risk
Abstract
Over the past year, we have identified an additional 241 cases diagnosed from 1999-2001 and 482 controls from the mammography practice and database at the Mayo Clinic. Together with the previous cases identified, we will have approximately 364 cases and 728 controls, instead of the initially proposed 200 cases and 400 controls. All mammograms over the last 10 years have been obtained for all cases to date and progress is continuing on obtaining the mammograms for the remaining controls. Risk factor information has been abstracted on all 364 cases and approximately 217 controls to date. Work on the remaining 511 controls is underway and will take approximately 1.5 additional years to complete. We performed early analyses of percent breast density and dense area from the earliest mammogram and absolute change between the earliest and latest mammograms with breast cancer risk on the 123 cases and 217 controls for which we had complete information to date. These data were presented at the American Association for Cancer Research meetings in April and also will be presented at the DOD meetings in September. The next two years will involve continuation of mammogram retrieval and digitization, chart abstraction, statistical analyses and report writing.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2002
- Accession Number
- ADA409690
Entities
People
- Celine M. Vachon
Organizations
- Mayo Clinic