Mechanisms of Virus-Induced Neural Cell Death

Abstract

Virtually all known neurotropic viruses are capable of killing infected cells by inducing a specific pattern of cell death known as apoptosis, yet the mechanism by which this occurs and its relevance to human disease remain largely unknown. We have shown that apoptosis is an important feature of human CNS viral infections including herpes simplex virus and cytomegalovirus encephalitis, and PML.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2002
Accession Number
ADA409696

Entities

People

  • Kenneth L. Tyler

Organizations

  • University of Colorado Health

Tags

DTIC Thesaurus Topics

  • Arteries
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel

Fields of Study

  • Biology

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Virology (or Medical Virology).