Injectable Sources of Locally Controlled Electrical Fields to Facilitate Tissue Repair

Abstract

Both pulsatile (AC) and continuous (DC) electrical fields have been reported to increase growth or healing or otherwise modify the structure of various tissues, including nerves, bones and skin. Systematic application of these techniques in both animal research and clinical treatment has been hampered by the limitations of currently available technology. We describe a new modular approach in which one or more wireless, microminiature, programmable current generators can be injected or implanted in a wide range of sites. Each device has its own address and can be powered and commanded via an external RF field to produce 10, 100 or 500 micronA DC and/or pulse trains of 0.2-30 mA at %512 microns duration. The implants are 2 mm in diameter and 16mm long. They are made from hermetically sealed, biocompatible materials, so they can be used indefinitely or left in situ after treatment is complete.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA409820

Entities

People

  • G. E. Loeb
  • H. M. Kaplan

Organizations

  • University of Southern California

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Autonomic Nervous System
  • Biocompatible Materials
  • Bone And Bones
  • Bone Fractures
  • Capacitors
  • Cells
  • Connective Tissue
  • Electromagnetic Fields
  • Electromagnetic Radiation
  • Health Services
  • Lithium Ion Batteries
  • Magnetic Fields
  • Materials
  • Osteogenesis
  • Peripheral Nervous System
  • Photoelectrochemical Cells
  • Wound Healing

Readers

  • Integrated Circuit Design and Technology.
  • Semiconductor Device Technology
  • Trauma Surgery or Emergency Medicine.