Cellular Sensing Devices for Assessing Chemicals

Abstract

Several types of cellular biosensors have been developed for assessing chemicals in which the cell responses to chemicals are transduced to the sensor outputs in various manners. The cell layer is fixed in the vicinity of the signal transducer. As an example assessment of immunomodulating chemicals has been performed with a cellular biosensor based on electrochemical determination of the inducible nitrogen oxide synthase (iNOS) expression in a macrophage-like cell.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA409961

Entities

People

  • E. Kobatake
  • K. Kamei
  • M. Aizawa
  • T. Haruyama

Organizations

  • Tokyo Institute of Technology

Tags

Communities of Interest

  • Sensors

DTIC Thesaurus Topics

  • Abstracts
  • Biosensors
  • Biotechnology
  • Cardiovascular Physiological Phenomena
  • Cell Membrane
  • Cells
  • Culture Techniques
  • Cultured Cells
  • Detection
  • Detectors
  • Endothelial Cells
  • Engineering
  • Immune System
  • Macrophages
  • Military Research
  • Nitrogen
  • Nitrogen Oxides

Fields of Study

  • Biology
  • Chemistry

Readers

  • Electrochemical Engineering/ Fuel Cell Technologies
  • Immunology and Pathology
  • Instructional Design and Training Evaluation.

Technology Areas

  • Biotechnology