Dynamic Simulations of Cancellous Bone Resorption Around Orthopaedic Fixative Implants

Abstract

Progressive loosening of bone fixation screws is a well documented phenomenon, induced by stress shielding and subsequent adaptive bone remodeling which results in bone loss around the screw. A set of two-dimensional computational (finite element) models was developed in order to test the effect of various screw profiles on the predicted extent of bone resorption. An algorithm simulating local bone adaptation to mechanical stimuli was developed and subsequently used to evaluate the biomechanical performances of the different screw profiles analyzed, i.e., triangular, rectangular and trapezoidal thread shapes. This remodeling algorithm predicted local bone gain or loss in the vicinity of the screw as a response to the resulted mechanical stress distribution. A dimensionless set of stress intensity parameters (SIP) was developed to quantify the bone screw stress transfer, enabling a convenient rating of different screw performances according to the nature of expected adaptation of the surrounding bone. The results indicated that a wide rectangular screw profile is of superior biomedical compatibility, with bone compared to the other profile types. The present work demonstrated that bone remodeling computer simulations can be used as a powerful tool for evaluation of different design parameters of fixative screws, such as geometry, material characteristics and even coatings.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA410019

Entities

People

  • A. Gefen

Organizations

  • Tel Aviv University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Engineering
  • Bone Diseases
  • Computer Simulations
  • Engineering
  • Fixatives
  • Geometry
  • Joints (Anatomy)
  • Modulus Of Elasticity
  • Musculoskeletal Physiology
  • Musculoskeletal System
  • Prostheses And Implants
  • Prosthetics
  • Screws
  • Simulations
  • Skeleton
  • Stiffness
  • Two Dimensional

Readers

  • Computational Modeling and Simulation
  • Electrical Engineering
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology