Investigating the Mechanisms of Action and the Identification of Breast Carcinogens by Computational Analysis of Female Rodent Carcinogens

Abstract

This project is investigating the potential that environmental estrogens may be involved in the etiology of breast cancer. We hypothesize that specific features of chemicals can be identified that are significantly associated with female and breast carcinogens and these features are related to mechanisms of chemical carcinogenesis. Our overall scientific objective is to investigate the hypothesized relationship between environmental chemicals, xenoestrogens, and the development of breast cancer. To date we have accomplished only part of Specific Aim 1 or basically less than six months of scheduled work. This is due to my leaving the University of Pittsburgh and joining the faculty at Louisiana State University. Due to administrative details beyond my control, the funds are now only expected to be reaching LSU in the near future. I factored in a no-cost extension for year one in the modified budget. Therefore, technically, year one is not over for this project.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2002
Accession Number
ADA410270

Entities

People

  • Albert R. Cunningham

Organizations

  • Louisiana State University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Carcinogens
  • Continents
  • Databases
  • Electronic Mail
  • Estrogens
  • Etiology
  • Geographic Regions
  • Identification
  • Information Operations
  • Louisiana
  • Neoplasms
  • United States
  • Universities

Readers

  • Academic Conference Management
  • Molecular and genetic basis of cancer.
  • Systems Analysis and Design