Effect of Segmented Polyurethane Coating on Thrombus Regulated With Pulsatile Shear Flow
Abstract
The effect of segmented polyurethane coating on thrombus formation was quantitatively studied under shear field in vitro. The Couette-type of shear rate was applied to the canine blood between the concave and the convex cones, Variation was made about materials of cones: Polymethyl-methacrylate, polyvinyl chloride, and polyvinyl chloride coated with segmented polyurethane The study shows that the clotting time extends on the segmented polyurethane especially at the higher shear rates, although the clot ratio is in the same level as that of without coating. This clotting time extension should regulate thrombus formation under pulsatile shear flow.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 25, 2001
- Accession Number
- ADA410431
Entities
People
- Atsushi Yamanaka
- Hajime Otani
- Shigehiro Hashimoto
- Yoshinori Murashige
Organizations
- Osaka Institute of Technology