Reconstruction of Mammary Gland Structure Using Three-Dimensional Computer-Based Microscopy
Abstract
During the last funding year, we have optimized the multi-resolution, multi-channel, three-dimensional reconstruction software developed during the first funding year. This required developing, optimizing and integrating automatic algorithms to substitute human interaction in labor-intense, highly repetitive tasks. Building up on a purely interactive system, we have developed new algorithms that eliminate or highly reduce the amount of interaction required for acquiring, registering, annotating and analyzing the images, thus reducing the time required for imaging tissue blocks from several weeks to several days. This is a prerequisite for our planned studies which require whole-gland, extended tissue analysis at multiple developmental stages.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2002
- Accession Number
- ADA410460
Entities
People
- Carlos O. De Solorzano
Organizations
- University of California, Berkeley