Robust Adaptive Control of Hypnosis During Anesthesia

Abstract

A closed-loop controller for hypnosis was designed and validated on humans at our laboratory. The controller aims at regulating the Bispectral Index (BIS) - a surrogate measure of hypnosis derived from the electroencephalogram of the patient - with the volatile anesthetic isoflurane administered with a closed-circuit breathing system. The control algorithm consists of a cascaded Internal Model Controller (IMC) where the master loop aims at regulating BIS. The slave loop tracks endtidal concentration references provided by the master controller. In this paper, a new tuning method is presented.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA410487

Entities

People

  • Andrea Gentilini
  • Manfred Morari
  • Pascal Grieder
  • Thomas W. Schnider

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Accuracy
  • Algorithms
  • Anesthesia
  • Classification
  • Control Systems
  • Engineering
  • Gaussian Noise
  • Guarantees
  • Identification
  • Measurement
  • Military Research
  • Noise
  • Respiratory System
  • Simulations
  • Transfer Functions
  • Uncertainty

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