2-D and 3-D Digital Analysis of Breast Calcifications: A Technique to Improve Mammographic Specificity
Abstract
A method of imaging breast calcifications in 3D was developed. The method is based upon the principles of limited-view image reconstruction. Each calcification is manually identified in multiple views of the breast, and is then semi-automatically segmented. The identified position in 3D is calculated geometrically. The segmented views of each calcification are used to generate a 3D model of each calcification. The calcifications are rendered with custom viewing software that can render the images stereoscopically. The technique has been shown to be capable of rendering calcifications as small as 100 micrometers, with an accuracy of approximately 100 micrometers. A clinical trial was conducted. In instances where calcifications are associated with a mass, we can distinguish preferentially peripherally distributed calcifications from homogeneously distributed calcifications.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2001
- Accession Number
- ADA410544
Entities
People
- Andrew D. Maidment
Organizations
- Thomas Jefferson University