Unidirectional Blocks and Ectopic FOCI Induced by Coupling an Ishemic and a Normal Ventricular Cell

Abstract

This study deals with the behavioral zones of a system composed of a normal myocardial cell (NC) coupled by an electric resistance R to an ischemic, depolarized by an added steady current I, (DC) cell. When varying I, we evidenced 3 levels of stationary solutions corresponding to low (L), medium (M) and high (H) values of the resting potential. In the L zone, we evidenced unidirectional block (LJB) effects with respectively 2 (R=20) or 1 (R=50) thresholds of depolarization, From 2 Hopf bifurcation points, emerge branches of periodic solutions corresponding to ectopic foci (EF) coexisting with L or M types of resting potential. In these zones, we found again UB effects with, in case of propagation, a locking of the system to a rhythmic activity. This theoretical study represents a unified approach of some types of UB and EF related to ischemia.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA410562

Entities

People

  • A. Bardou
  • M. Landau

Organizations

  • National Center for Scientific Research

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amplitude
  • Cardiac Arrhythmias
  • Classification
  • Couplings
  • Demographic Cohorts
  • Depolarization
  • Ischemia
  • Mathematical Models
  • Military Research
  • Models
  • Resistance
  • Stationary
  • Unidirectional

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Control Systems Engineering.
  • Theoretical Analysis.