Exact Test Size and Power for Small Samples Using an Internal Pilot Study
Abstract
Marlar and Welsh (2001) proposed a prospective ascertainment strategy for a case-control study of deep venous thrombosis with a binary exposure. This study design relied on prevalence estimates of certain genetic polymorphisms from previous studies using different populations. They planned on collecting a portion of the data to use as an internal pilot in order to better estimate these prevalences using their population of interest. The internal pilot data were used to estimate the population prevalences and recalculate the required sample size. All the data, including the internal pilot data, were used in the final analysis. They used a x(2) to analyze the resulting 2 x 2 table. We have been unable to find a paper in which the authors considered power and sample size for a case-control study with an internal pilot study.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 31, 2003
- Accession Number
- ADA410777
Entities
People
- Timothy S. Webb
Organizations
- Air Force Institute of Technology