Genetic Regulatory Networks: Analysis and Simulation
Abstract
The objective of this research is to understand how genetic regulatory circuits function. The behavior of genetic regulatory networks in bacterial cells is analyzed using computer-based simulations of molecular-level models, positional information from observation of GFP-labeled regulatory molecules, and gene expression data from microarray assays of wild-type and mutant Caulobacter cells. A new view of the cell cycle as a sequence of modular functions controlled by a few networked master regulatory proteins challenges former paradigms for how the cell works and how to model cell function.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 21, 2003
- Accession Number
- ADA410805
Entities
People
- Harley Mcadams
Organizations
- Stanford University