Preliminary Study on the Oxygen Consumption Dynamics During Brain Hypothermia Resuscitation

Abstract

Based on the classical Pennes bioheat equation and oxygen diffusion equation, a new coupled heat-mass transfer model for characterizing the cerebral circulatory arrest is proposed. Two cooling approaches (the surface cooling and volumetric cooling are applied to analyze the effect of hypothermia on the transient temperature and the oxygen consumption rate in different regions of brain. it is shown that the surface cooling contributes little to depress the oxygen consumption, which received few attentions before. As an alternative, the volumetric cooling win significantly reduce the oxygen consumption rate In the brain, thus prolong the patients' survival time. The results, which are close in agreement with the previous experimental data, may aid to find more efficient treatments on the brain hypothermia resuscitation.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA410834

Entities

People

  • Jing Liu
  • Yan Ji

Organizations

  • Chinese Academy of Sciences

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Air Temperature
  • Blood
  • Cardiac Arrest
  • Cardiovascular System
  • Chemistry
  • Coefficients
  • Cooling
  • Diffusion
  • Diffusion Coefficient
  • Equations
  • Heat Transfer
  • Perfusion
  • Rate Of Consumption
  • Surgery
  • Temperature Coefficients
  • Thermal Conductivity
  • Water Cooling

Readers

  • Environmental Engineering
  • Fluid Dynamics.
  • Trauma Surgery or Emergency Medicine.