Electrical Impedance Imaging of the Breast: Correlation With MRI, US, Sestamibi and Histology With Measures of Cell Proliferaton and Vascular Density

Abstract

This project was designed to test a new method for the evaluation of lesions suspected as possible cancers after their initial detection. Electrical Impedance Imaging (EII) is a novel method for the evaluation of breast lesions that relies on measurements of the electrical impedance and capacitance of breast tissues. It showed, in previous trials, good ability to distinguish benign and malignant lesions. The system received FDA approval 4/16/99. The work on this project was delayed because we have not yet received concurrent approval from the Georgetown IRB and the US Army to start the clinical trial. A revised protocol had passed the Georgetown IRB review, but on US Army Human Subjects review, additional changes were requested. These will be submitted shortly. Because the system is FDA approved, we have used it both clinically and in other clinical trials and have discovered that the system is not ready for the type of use originally proposed.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2002
Accession Number
ADA410879

Entities

People

  • Matthew L Freedman

Organizations

  • Georgetown University

Tags

Communities of Interest

  • Advanced Electronics
  • Engineered Resilient Systems

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Carcinoma
  • Databases
  • Detection
  • Detectors
  • Dielectric Permittivity
  • Electrical Impedance
  • Electrical Properties
  • Electricity
  • Health Services
  • Histology
  • Impedance
  • Institutional Review Board
  • Medical Personnel
  • Physicians

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Medical Imaging.
  • Oncology and Biomarker-Based Cancer Detection.