Enhanced T Cell Attack of Brain Micro-Metastases
Abstract
Brain-metastasizing breast cancer is a major clinical problem. Cell-mediated immunotherapy is well-suited to attack it, but the efficacy must be increased. We developed a rat model and began to test our proposed therapy. A key step is to inject gamma interferon (IFN-g) into the brains of rats with metastatic mammary carcinoma. During the period of this report, technical and theoretical problems were identified and addressed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2002
- Accession Number
- ADA410926
Entities
People
- Lois A. Lampson
Organizations
- Brigham and Women's Hospital