Characterization of the Metabolism, Distribution and Toxicity of 2,6-di-t-Butyl-4-Nitrophenol for Purposes of Health Hazard Assessment

Abstract

In 1992, the Navy Environmental Health Center, Norfolk, VA was made aware of the concern about the discoloration (yellowing) of interiors (e.g. bulkheads and bedding) and the possible exposure of navy personnel aboard submarines, to an - unknown substance. The agent was identified as 2,6-di-tert-butyl-4-nitrophenol (DBNP). The yellowing process appeared to arise from the reaction of 2,6-di-tert-butylphenol (DBP), an antioxidant additive used in engine lubricant, with NO2 in the submarine atmosphere. A research program was initiated for health hazard assessment of DBNP. - This technical report summarizes the results of our research program and the information available in the literature.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1997
Accession Number
ADA411058

Entities

People

  • A. E. Jung
  • K. R. Still
  • R. L. Carpenter
  • S. Prues
  • T. K. Narayanan

Organizations

  • Naval Medical Research Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohols
  • Biliary Tract
  • Biomedical Research
  • Chemical Synthesis
  • Chemistry
  • Chlorides
  • Chromatography
  • Crystal Structure
  • Liquid Chromatography
  • Medical Personnel
  • Metabolism
  • Phenols
  • Rodents
  • Toxicity
  • Toxicology
  • Veins

Readers

  • Analytical Chemistry
  • Aviation Safety Risk Assessment.
  • Fire Suppression Systems Design.