Metabolizing Enzyme Polymorphisms and Prognosis Among Women Treated for Breast Cancer

Abstract

This study will use archived tissue and data to examine survival of women treated for breast cancer in relation to inherited polymorphisms of drug metabolizing enzymes. During the first year of funding, we have completed compilation of tumor registry data for eligible subjects (Task 1 of the approved statement of work). We have also completed study start-up tasks, including IRB review, hiring study staff, creating data collection forms, establishing a study database, and training study staff on data collection procedures. Collection of tissue samples (Task 2 of the approved statement of work) has begun. Activities currently in progress include obtaining pathology slides and blocks, review of slides by the study pathologist, and abstracting information from pathology reports into the study database. As described in the statement of work, data collection tasks will continue into years 2 and 3, so no reportable scientific results are available at the end of year 1.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2002
Accession Number
ADA411547

Entities

People

  • Carol Sweeney

Organizations

  • University of Minnesota

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Alkylating Agents
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Data Analysis
  • Databases
  • Department Of Defense
  • Employment
  • Enzymes
  • Medical Personnel
  • Neoplasms
  • Pathology
  • Personnel Management
  • Physicians
  • Survival
  • Training

Readers

  • Molecular and genetic basis of cancer.
  • Oncology and Biomarker-Based Cancer Detection.
  • Technical Research and Report Writing.