Spatiotemporal Dynamics of Pacing in Models of Anatomical Reentry

Abstract

Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However the mechanisms of termination (success and failure) are poorly understood. To elucidate such mechanisms, we studied pacing of anatomical reentry in 1-D and 2-D excitable cardiac media models. Our results suggest that the existence of inhomogeneity in the reentry circuit is essential for pacing termination of tachycardia to be successful. Considering the role of such inhomogeneities may lead to more effective pacing algorithms.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA411598

Entities

People

  • David J. Christini
  • Sitabhra Sinha

Organizations

  • Weill Cornell Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Boundaries
  • Cardiology
  • Classification
  • Conductivity
  • Dynamics
  • Gray Scale
  • Ionic Current
  • Military Research
  • Myocardial Ischemia
  • New York
  • Schematic Diagrams
  • Simulations
  • Subatomic Particles
  • Universities
  • Wave Propagation

Fields of Study

  • Biology

Readers

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  • Trauma Surgery or Emergency Medicine.
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