Magnetic Resonance Spectroscopy Imaging and Functional Magnetic Resonance Imaging of Neurofibromatosis Type 1: In Vivo Pathophysiology, Brain-Behavior Relationships and Reading Disabilities

Abstract

The purpose of this research is oriented towards understanding the reading, language, and articulation deficits associated with Neurofibromatosis Type 1 (NF-1) and relating these deficits to the underlying pathophysiology of NF-1 as revealed by Magnetic Resonance Spectroscopy Imaging (MRSI). A second goal is to determine how differences in activation, as measured by functional Magnetic Resonance Imaging (fMRI), are linked to the cognitive/academic impairments associated with NF-1. A third goal is to further understand how T-2 weighted hyperintensities on Magnetic Resonance Imaging (MRI) scans are related to cognitive/academic impairments associated with NF-1.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2002
Accession Number
ADA411678

Entities

People

  • Alena Horska
  • Christine W. Koth
  • Laurie E. Cutting
  • Peter Barker
  • Walter Kaufmann

Tags

DTIC Thesaurus Topics

  • Brain
  • Brain Injuries
  • Central Nervous System
  • Cognition
  • Diseases And Disorders
  • Genetic Disorders
  • Health Services
  • Information Science
  • Language
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Mental Processes
  • Neuroimaging
  • Neurosciences
  • Regression Analysis
  • Statistical Analysis

Readers

  • Medical Imaging.
  • Molecular and Cellular Biology
  • Neuroscience