In Vitro Determination of Skin Bilirubin Using Chromatic Modulation

Abstract

A clinical examination system is presented to analyse the yellowness presented on the skin of premature newborn babies, namely transcutaneous bilirubin (TcB). The system is based on chromatic modulation methods to extract, process and analyse data in order to determine the spectral chromaticity of a baby's tissue without taking blood samples. Chromatic bilirubin monitoring tests have shown a high correlation and a linear relationship between serum bilirubin (SB) and a chromatic parameter, namely Hue angle (H). The chromatic TcB results are highly predictive of SB levels in neonatal babies. The proposed chromatic system can be used to make decisions about transfusions or phototherapy in neonates, hence acting as a screening device to determine when a laboratory measurement of SB is needed.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA411830

Entities

People

  • D. Tomtsis
  • D. Zissopoulos
  • V. Kodogiannis

Tags

Communities of Interest

  • Energy and Power Technologies
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Abstracts
  • Bile Pigments
  • Bilirubin
  • Blood
  • Calibration
  • Chromaticity
  • Clinical Laboratories
  • Computer Programs
  • Computers
  • Detectors
  • Diseases And Disorders
  • Health Services
  • Light Sources
  • Measurement
  • Medical Personnel
  • Personal Computers
  • Visible Spectra

Fields of Study

  • Medicine

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