Optical Proteinchip as Microarrays for Protein Interaction Determination

Abstract

One kind of optical protein chip and a ProteinChip analysis system have been introduced, The chip is processed with surface patterning, surface modification, ligand immobilization to form a sensing surface with multi-bioactivity The affinity between proteins is used to realize non-labeling micro-assays for protein identifications and protein interactions, A model of the chip and some demonstration results are presented,

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA411904

Entities

People

  • G. Jin
  • L. H. Xia
  • P. Q. Ying
  • Y. H. Meng
  • Z. H. Wang

Organizations

  • Chinese Academy of Sciences

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Albumins
  • Antibodies
  • Detection
  • Imaging Techniques
  • Immune Serums
  • Immunoglobulins
  • Military Research
  • Molecules
  • Monomolecular Films
  • Numbers
  • Photolithography
  • Proteins
  • Sampling
  • Self Assembly
  • Square Roots
  • Substrates
  • Thickness

Readers

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  • Molecular and Cellular Biochemistry
  • Oncology and Biomarker-Based Cancer Detection.