Protein-Assisted Redox Sensing at Biomimetic Electrode
Abstract
Sarnoff is developing a biomimetic protein-assisted redox sensing system based on the organized molecular pathways found in nature. This system makes use of a biomimetic membrane coated on a gold electrode as a bio-electronic interface. This membrane will enable the nondissipative conversion of a redox event occurring in an aqueous medium to an electrical signal. The nondissipative conversion is enabled by lipid chains functionalized with prosthetics groups that are organized to mimic concerted, vectorial electron transfer. In this program, Sarnoff has designed and synthesized electron transfer molecules, and engineered them into an organized self-assembled membrane (SAM). We have demonstrated the vectorial transfer of electrons from a biofluid (aqueous) solution to an electrode using this membrane. We also functionalized the SAM with proteins to demonstrate the sensing of redox reaction in aqueous solution.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 2003
- Accession Number
- ADA412000
Entities
People
- Jia Chen
- Yongchi Tian
Organizations
- Sarnoff Corporation