Optimization of Breast Cancer Treatment by Dynamic Intensity Modulated Electron Radiotherapy

Abstract

Three specific work projects were pursued during the first year of this grant: 1) Static electron fields defined by the photon MLC were measured. Beam profiles and output factors at distances of 75, 85 and 100 cm SSD were measured for fields from 1 cm to 20 cm wide. Measurements were made for electron energies of 6, 9, 12, 16 and 20 MeV. Profiles were compared vs. energy, and their departure from strictly divergent fields was noted. Profiles defined by the MLC were compared with previous profiles defined by cerrobend(Trademark) apertures. 2) Monte Carlo techniques were applied to 3D electron dose calculations. The rounded shape of the MLC ends, the long air scatter column, and the reduced density air at Utah altitude were addressed in the calculations. Excellent agreement was achieved compared to measured profiles and.measured relative output factors. The Monte Carlo calculations correctly account for air scatter effects vs. field size and SSD, and correctly predict relative output factors vs. field size and SSD. 3) An iterative optimization technique to determine the required MLC leaf positions vs. arc rotation was defined. The work to date is on track for successful completion of the project within the grant period.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2002
Accession Number
ADA412101

Entities

People

  • David K. Gaffney
  • Dennis D. Leavitt

Organizations

  • University of Utah

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Algorithms
  • Breast Cancer
  • Electron Beams
  • Electron Energy
  • Electron Scattering
  • Electrons
  • Energy
  • Intensity
  • Ionization Chambers
  • Measurement
  • Neoplasms
  • Optimization
  • Radiotherapy
  • Scattering
  • Therapy
  • Three Dimensional
  • Two Dimensional

Fields of Study

  • Medicine
  • Physics

Readers

  • Computational Modeling and Simulation
  • Mathematics or Statistics
  • Solar Physics

Technology Areas

  • Microelectronics
  • Microelectronics - Microelectromechanical Systems