An LOH Study of Chromosome 8 in Multiplex Prostate Cancer Sibships

Abstract

This study was designed to identify one or more prostate cancer (CaP) tumor suppressor genes (TSG) on chromosome 8 by assessing the distribution of loss of Heterozygosity (LOH) in brothers from multiplex sibships A strong linkage signal as been demonstrated in these families. LOH was assessed in 202 men with histologically confirmed prostate cancer.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2002
Accession Number
ADA412237

Entities

People

  • Brian K. Suarez

Organizations

  • Washington University in St. Louis

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Biomedical Research
  • Blood
  • Cancer
  • Cells
  • Chemistry
  • Chromosomes
  • Colon Cancer
  • Computers
  • Diseases And Disorders
  • Genetic Code
  • Genetic Structures
  • Genetics
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Prostate Cancer

Readers

  • Molecular and genetic basis of cancer.
  • Oncology and Biomarker-Based Cancer Detection.