Transgenic Models for Prostate Cancer

Abstract

During phase II of this IDEA Award, our current focus is to study genes/pathways implicated in prostate cancer progression using transgenic mouse models. Our efforts have focused on creating transgenic models that express 1 of 4 different genes in the mouse prostate. All 4 genes were selected based on studies from our lab and others implicating these genes in human prostate cancer. These include Her-2/neu, cathepsin D, Akt and Myc.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2002
Accession Number
ADA412836

Entities

People

  • Charles Sawyers

Organizations

  • University of California, Los Angeles

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Androgen Receptors
  • Biological Factors
  • Cancer
  • Carcinoma
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Liquid Chromatography
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Prostate Cancer
  • Proteins
  • Tissues

Fields of Study

  • Biology

Readers

  • Oncology (Cancer Research).