Low Melatonin Production During Adulthood: A Possible Genetic Susceptibility Factor for Breast Cancer Incidence

Abstract

The study has been given a 1-year no cost extension - until September 30, 2003. To date, there have been 188 urine samples and epidemiologic questionnaires collected from 61 families. Ninety-seven (97) urines samples have been run to assay overnight melatonin metabolite and creatinine production. Two 96-well kits have been purchased for the remaining samples and those to be obtained during this extension year. Melatonin and creatinine production data for the 97 subjects, representing 28 families, have been computerized and edited. Preliminary computer analyses have been conducted. The database for the epidemiologic questionnaire data has been established and data have begun to be computerized. There are additional families who have agreed to participate, but for whom a convenient time to collect the data has not been determined. Families are continuing to be recruited.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2002
Accession Number
ADA412881

Entities

People

  • Eugene Sobel
  • Floyd H. Gilles
  • Zoreh Davanipour

Organizations

  • University of Southern California

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breast Cancer
  • California
  • Classification
  • Creatinine
  • Melatonin
  • Neoplasms
  • Production
  • Questionnaires
  • Security
  • Urine

Readers

  • Clinical Trial Research.
  • Molecular and genetic basis of cancer.
  • Software Engineering

Technology Areas

  • Biotechnology