Mathematical Model and Experimental Design for Human IgG Diffusion

Abstract

A model of human IgG diffusion is presented. With the aid of computer based simulation, it will help members of the consortium of the EU funded project "Tissue engineered nerve repair devices: development of European medical implantable devices and research training focus" to predict the incorporation/release diffusion dynamics of soluted, including therapeutic antibody, in engineered tissues. The experimental design which will be used to identify the model parameters is also presented with the first experimental results.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 2001
Accession Number
ADA412978

Entities

People

  • C. Ruggiero
  • I. Peragallo
  • M. Giacomini
  • S. Bertone

Organizations

  • University of Genoa

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Antibodies
  • Chemical Properties
  • Detection
  • Diffusion
  • Diffusion Coefficient
  • Engineering
  • Experimental Design
  • Literature Surveys
  • Macromolecules
  • Materials
  • Mathematical Models
  • Models
  • Molecules
  • Polymers
  • Simulations
  • Tissues

Readers

  • Computational Modeling and Simulation
  • Immunology
  • Trauma Surgery or Emergency Medicine.