Magnetic Resonance Arterial Spin Tagging for Non-Invasive Pharmacokinetic Analysis of Breast Cancer

Abstract

This research project focused on the development of MRI arterial spin tagging to non-invasively measure breast tissue perfusion. The specific aims were to (1) refine arterial spin tagging pulse sequences, (2) develop automated data analysis software, and (3) compare the technique to first-pass contrast-enhanced MRI and biopsy. New spin-tagging pulse sequences were developed for the GE 1.5T Advantage and Horizon LX CV/I MRI systems, and new image processing software, including software for statistical analysis of spin tagging and contrast enhanced dynamic scans, were written for use in the clinical setting. Year three and no-cost extension years of the project focused on clinical comparison of arterial spin tagging with first-pass, contrast-enhanced MRI in patients with unbiopsied breast masses, for aim.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2002
Accession Number
ADA413282

Entities

People

  • Michael H. Buonocore

Organizations

  • University of California

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Cancer
  • Coding
  • Computational Science
  • Computer Programming
  • Computer Programs
  • Computers
  • Data Acquisition
  • Data Analysis
  • Data Processing
  • Electronic Mail
  • Health Services
  • Image Processing
  • Magnetic Resonance
  • Medical Personnel
  • Operating Systems
  • Statistical Analysis

Fields of Study

  • Physics

Readers

  • Medical Imaging.