Signal Transduction Based Mouse Models of Prostate Cancer

Abstract

These studies aimed to create a prostate cancer mouse model consortium. The overall objective of this study is to determine the mechanisms governing prostate cancer genesis and progression thereby leading to a better understanding and treatment for this disease. The studies brought together investigators at distinct institutions (Albert Einstein College of Medicine (AECOM) Memorial Sloan Kettering Cancer Center (MSKCC), Beth Israel Deaconess Medical Center- Harvard/Massachusetts Institute of Technology Health Sciences and Technology, HMS/MIT) and UC Davis to develop and share a) mouse models engineered through sharing distinct models generated by each program member b) software technology that will allow for the simultaneous analysis of histopathology and genetic composition of the emerging murine prostate tumors at the different institutions c) software technology for functional clustering of data derived from microarray analysis of tumor samples.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2003
Accession Number
ADA413570

Entities

People

  • Richard Pestell

Organizations

  • Albert Einstein College of Medicine

Tags

DTIC Thesaurus Topics

  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Genetics
  • Health Services
  • Peptides
  • Prostate Cancer
  • Proteins

Readers

  • Molecular Biology and Genetics
  • Oncology
  • Research Science/Academic Research

Technology Areas

  • Biotechnology