Intra- and Inter-Species Communication in the Marine Environment

Abstract

The long-term goal of this research is to explore the molecular mechanisms that marine bacteria use for intra-species and inter-species cell-cell communication. To do this we will investigate the functions controlled by the two quorum sensing signalling pathways of the model luminous bacterium Vibrio harveyi. We have shown that V. harveyi uses Signalling System 1 for intra-species communication and Signalling System 2 for inter-species cell-cell communication. We will identify target genes that are regulated exclusively by System I and System 2, and those target genes that are jointly controlled by both Systems. Our analysis of this regulatory network will lead to a molecular understanding of how bacteria integrate, process and transduce sensory information to control gene expression in response to inter-cellular communication.

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Document Details

Document Type
Technical Report
Publication Date
Apr 30, 2003
Accession Number
ADA413807

Entities

People

  • Bonnie L. Bassler

Organizations

  • Princeton University

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Bacteria
  • Cell Physiological Processes
  • Cells
  • Communication Systems
  • Detectors
  • Electron Density
  • Electrons
  • Environment
  • Gene Expression
  • Gram-Positive Bacteria
  • Hydrogen Bonds
  • Identification
  • Microbiology
  • Mobile Communications
  • Molecular Biology
  • Molecules
  • Proteins

Fields of Study

  • Biology
  • Environmental science

Readers

  • Microbial Pathology
  • Molecular Biology and Genetics
  • Tactical Satellite Communications Systems Engineering.