Mixing and Processing of Complex Biological Fluids

Abstract

The primary deliverables for this research project have been the ability to predict the characteristics of the flow of complex biological fluids including viscoelastic fluids and blood, and the effect of microfluidic control on the makeup and molecular structure of biological fluids. For this project, we focused on two critical fluids that are biologically significant and that are of critical importance to DoD: DNA-laden fluids for early identification and diagnosis of pathogens, and blood for on-field reconstitution of whole blood from stabilized components. In addition to experimental investigations of complex fluid flows, computational and modeling capabilities have also been developed. The experimental results have been used to validate modeling tools at both Berkeley/LBL and at CFD Research Corporation. New capabilities for BioMEMS microelectricmicrofluidics design have been added to the commercial computational tools available from CFD Research Corporation as a result of this project.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2003
Accession Number
ADA414038

Entities

People

  • Dorian Liepmann

Organizations

  • University of California, Berkeley

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Blood Flow
  • Check Valves
  • Computational Fluid Dynamics
  • Corporations
  • Fabrication
  • Flow
  • Flow Rate
  • Fluid Dynamics
  • Fluid Flow
  • Measurement
  • Mechanics
  • Microelectromechanical Systems
  • Molecular Structure
  • Optics
  • Shear Flow

Readers

  • Computational Fluid Dynamics (CFD)
  • Molecular and Cellular Biochemistry
  • Trauma Surgery or Emergency Medicine.