Trace Elements and the Development of Prostate Cancer

Abstract

Selenium is an essential nutrient that may have an important preventive action in prostate cancer. We have identified a human gene in prostate cells, designated hSP56, the mouse homologue of which may mediate selenium's growth inhibitory effect in vitro and anti-cancer effect in vivo hSP56 is expressed by LNCaP but not by PC-3 and is reversibly downregulated by androgen.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2003
Accession Number
ADA414786

Entities

People

  • Arthur J. Sytkowski

Organizations

  • Beth Israel Deaconess Medical Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Androgens
  • Antibodies
  • Apoptosis
  • Biomedical Research
  • Carrier Proteins
  • Cell Line
  • Cells
  • Chemistry
  • Elements
  • Genetic Code
  • Neoplasms
  • Organoselenium Compounds
  • Prostate
  • Prostate Cancer
  • Proteins
  • Tissues

Fields of Study

  • Biology

Readers

  • Immunology
  • Prostate Cancer Biology.