Elastin Bioelastomers for Microactuation

Abstract

Stimuli-responsive elastin-like polypeptides (ELPs) with controlled polymer architectures were synthesized by recombinant DNA techniques, and the structure-property relationships and force transduction in crosslinked gels of these biopolymers were investigated as a function of their phase transition behavior. These studies provide design rules for the rational fabrication of ELP-based microactuators that function in aqueous environment to meet ONR objectives.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2002
Accession Number
ADA415591

Entities

People

  • Ashutosh Chilkoti

Organizations

  • Duke University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Engineering
  • Biopolymers
  • Deoxyribonucleic Acids
  • Fabrication
  • High Temperature
  • Low Temperature
  • Materials
  • Mechanical Properties
  • Molecular Weight
  • Phase Transformations
  • Physical Properties
  • Polymers
  • Prostheses And Implants
  • Recombinant Dna
  • Transition Temperature
  • Transitions

Fields of Study

  • Chemistry

Readers

  • Integrated Circuit Design and Technology.
  • Nanocomposite Materials Science
  • Oncology (Cancer Research).