Phage Fab Display Selection In Vitro and In Vivo: Novel Means to Identify New Breast Cancer Avid Compounds
Abstract
Breast cancer is the number one cause of death amongst cancer in women. New methods for early detection, diagnosis and treatment of cancer are always sought. In this report we show ongoing progress in the use of phage display libraries to isolate peptides and antibody fragments that target tumor material in an in vivo setting. Specifically we address the isolation of a number of phage peptide sequences and note that those isolated appear to be non specific and bind or stick' to non-tumor material. Further investigation is needed to determine if this is indeed the case.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2003
- Accession Number
- ADA415809
Entities
People
- Mark A. Meighan
Organizations
- University of Missouri