A Novel High-Resolution Positron Emission Tomography System for Measurement of Bone Metabolism

Abstract

The purpose of the work reported here is to develop high-resolution PET instrumentation for imaging the long bones. To-date a single plane prototype and a single plane second-generation instrumentation have been completed. The latter is currently being evaluated. A generalized multi-planar detector element has also been designed and evaluated experimentally and a volumetric instrument has been designed through simulation studies. A radiopharmaceutical for bone growth rate imaging, labeled C-tetracycline 11 has been developed for use in a demonstration study of imaging in a monkey osteoporosis model.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2002
Accession Number
ADA416011

Entities

People

  • John A. Correia

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Air Platforms
  • Biomedical

DTIC Thesaurus Topics

  • Acetonitrile
  • Chemical Synthesis
  • Data Acquisition
  • Detectors
  • Diagnostic Imaging
  • Health Services
  • High Resolution
  • Imaging Techniques
  • Instrumentation
  • Measurement
  • Operating Systems
  • Positron Emission Tomography
  • Positron Emissions
  • Positrons
  • Production Engineering
  • Prototypes
  • Tomography

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Systems Analysis and Design