Peptide Nanofilament Engineering

Abstract

This laboratory studied four systems involving molecular self-assembly during this project period. Each system will open a new avenue of research in developing novel applications for use in biomedical engineering and materials science. These systems include self-assembling oligopeptides that form stable beta sheets in water, peptides that form inter- and intramolecular self-assemblies, peptides that spontaneously assemble onto a surface to form monolayers, and peptides that condense and encapsulate DNA to facilitate highly efficient gene delivery. (2 figures, 12 refs.)

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Document Details

Document Type
Technical Report
Publication Date
Jul 04, 2003
Accession Number
ADA416701

Entities

People

  • Alexander Rich
  • Shuguang Zhang

Organizations

  • Massachusetts Institute of Technology

Tags

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Amino Acids
  • Assembly
  • Biomaterials
  • Biomedical Engineering
  • Biosensors
  • Engineering
  • Gene Delivery
  • Materials
  • Materials Laboratories
  • Materials Science
  • Molecules
  • Monomolecular Films
  • Nanomaterials
  • Nanotechnology
  • Peptides
  • Self Assembly

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology