Breast Cancer Detection and Management Using 3D Quantitative Ultrasonic Diffraction Tomography
Abstract
The broad objective of the proposed project is to investigate, develop, and evaluate the application of three-dimensional (3D) ultrasonic diffraction tomography (UDT) for detection of breast cancer. UDT can be viewed as a generalization of X-ray tomography where X-rays have been replaced with an acoustical wavefield. It can determine refractive index distributions within the breast that are of interest clinically and can be an excellent imaging modality for breast cancer because it can provide important information complementary to that obtained from mammograms and because it is non-invasive, free of radiation hazard, and reproducible. While UDT promises several potentially important advantages over conventional ultrasonic imaging and has found important uses in a wide variety of engineering and scientific disciplines, its application to breast imaging still remains largely unexplored. In the last year, our research on this project has, we believe, been successful and productive. We have investigated, developed, and evaluated computationally efficient and statistically optimal algorithms for accurate reconstruction of UDT images that may find applications in UDT imaging of breast cancer. We have made contributions to UDT research, as summarized in the report, by addressing numerous scientific and engineering problems involved in UDT image reconstruction. These results are necessary in making UDT a viable medical technique for imaging of breast cancer.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2002
- Accession Number
- ADA417000
Entities
People
- Xiaochuan Pan
Organizations
- University of Chicago