Policies for Biodefense Revisited: The Prioritized Vaccination Process for Smallpox

Abstract

Handling bioterror events that involve contagious agents is a major concern in the war against terror, and is a cause for debate among policymakers about the best response policy. At the core of this debate stands the question which of the two post-event policies to adopt: mass vaccination--where maximum vaccination capacity is utilized to uniformly inoculate the entire population, or trace (also called ring or targeted) vaccination--where mass vaccination capabilities are traded off with tracing capabilities to selectively inoculate only contacts (or suspected contacts) of infective individuals. We present a dynamic epidemic-intervention model that expands previous models by capturing some additional key features of the situation and by generalizing some assumptions regarding the probability distributions of inter-temporal parameters. The model comprises a set of difference equations. The model is implemented to analyze alternative response policies. It is shown that a mixture of mass and trace vaccination policies-the prioritized vaccination policy-is more effective than either of the two aforementioned policies.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2003
Accession Number
ADA417598

Entities

People

  • Moshe Kress

Organizations

  • Naval Postgraduate School

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Difference Equations
  • Differential Equations
  • Diseases And Disorders
  • Equations
  • First Responders
  • Health
  • Health Care
  • Health Services
  • Medical Personnel
  • Operations Research
  • Poxviridae Infections
  • Probability
  • Probability Distributions
  • Public Health
  • Random Variables
  • Situational Awareness
  • Vaccination

Readers

  • Infectious Disease/Epidemiology
  • Life Cycle Cost Analysis
  • Military History / Militaries and War Studies

Technology Areas

  • Biotechnology