Digital Filters for Gene Prediction Applications

Abstract

It has been observed by many researchers that the protein-coding regions of DNA sequences exhibit a period-3 behavior due to codon structure. Identification of the period-3 regions helps in predicting the gene locations and in fact allows the prediction of specific exons within the genes of eucaryotic cells. Traditionally these regions are identified with the help of techniques such as the windowed DFT. In this paper we consider the use of efficient digital filters for the same purpose. The filters can be designed not only to extract the period-3 component, but at the same time effectively eliminate the background 1/f spectrum exhibited by nearly all DNA sequences.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2002
Accession Number
ADA417660

Entities

People

  • Byung-jun Yoon
  • Palghat Vaidyanathan

Organizations

  • California Institute of Technology

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Amino Acids
  • Background Noise
  • Bandpass Filters
  • Computational Complexity
  • Computer Programming
  • Digital Filters
  • Filters
  • Filtration
  • Frequency
  • Indicators
  • Narrowband
  • Noise
  • Notch Filters
  • Quality Control
  • Sequences
  • Spectra
  • Sugar Phosphates

Fields of Study

  • Engineering

Readers

  • Approximation Theory.
  • Molecular Genetics
  • Theoretical Analysis.