Design and Construction of Genetic Applets

Abstract

In this Project, we took a forward engineering approach to understanding and controlling gene expression. Specifically, we developed a theory of gene networks that will execute a prescribed series of cellular functions. By designing the gene networks ourselves, we can allow only simple interactions and thus avoid the enormous complexity that biology has developed over years of evolution. This project involved both theoretical and experimental work.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2003
Accession Number
ADA417910

Entities

People

  • James J. Collins

Organizations

  • Boston University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bioengineering
  • Biology
  • Cell Physiological Processes
  • Coliphages
  • Construction
  • Engineering
  • Escherichia Coli
  • Gene Expression
  • Gene Therapy
  • Genetics
  • Oscillation
  • Oscillators
  • Personal Information Managers
  • Relaxation Oscillators
  • Switches
  • Switching
  • Toggle Switches

Fields of Study

  • Biology
  • Computer science

Readers

  • Database Systems and Applications
  • Molecular Genetics
  • Systems Analysis and Design

Technology Areas

  • Biotechnology