Low Vision Research at the Schepens Eye Research Institute

Abstract

This research proposal, Low Vision at the Schepens Eye Research Institute, is a collaborative effort on the part of four Investigators at the Institute whose goal is to advance the studies on low vision. Project 1 focuses on the promotion of corneal transplant longevity using targeted delivery of anti-apoptotic genes and has successfully delivered the desirable genes into corneal explants. Project 2 involves studies on biodegradable polymers and CNS stem cells, and has been able to incorporate CNTF and GDNF in slow release biopolymers which they have tested in mouse models. Project 3 encompasses research on photoprotection by macular pigment and tests the hypothesis that macular pigment protects the retina from damage leading to degradation of macular function. Project 4 is a continuation of the remote diagnosis of retinal damage; the initial instrument design for the testing of human subjects is completed. Project 5 is also a continuation of the identification of factors that can predict dry eye complications of LASIK surgery. Patient enrollment is proceeding well and early analyses are complete.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2003
Accession Number
ADA417960

Entities

People

  • Patricia A. D'amore

Organizations

  • Schepens Eye Research Institute

Tags

DTIC Thesaurus Topics

  • Cell Physiological Processes
  • Cells
  • Cornea
  • Eye Diseases
  • Health Services
  • Medical Personnel
  • Ophthalmology
  • Proteins
  • Retinal Diseases
  • Stem Cells
  • Surgery
  • Transplants
  • Vision Disorders

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Technical Research and Report Writing.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Biotechnology