Magnetic Resonance and Spectroscopy of the Human Brain in Gulf War Illness

Abstract

The goal of this project is to test the hypotheses that: 1.) Subjects with GWI have reduced NAA in the basal ganglia and pons, which are not accounted for by confounds such as depression, post traumatic stress disorder, and alcoholism. 2.) Reduced NAA in basal ganglia and pons correlates with CNS signs and symptoms of GWI. Thus far we have mailed out a total of 505 letters describing our study. Dr Weiner appeared on several radio and TV programs, in response to our press release. Over 262 subjects have contacted us expressing interest in this study. Since we began enrolling subjects, we have largely met our goals of studying 2 subjects/week with the complete study battery which includes medical evaluation, neuropsychological testing, startle testing, MRI/MRS and the "Haley Questionnaire." Thus far, we have studied a total of 84 subjects. At this time, 22 of these subjects have met the criteria for GWI and 26 are controls, with 36 having an intermediate classification. We currently have 5 subjects scheduled for study for the remainder of the month. Although some preliminary data analysis has been performed, at the current time the sample size is much too small for any formal data analysis.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2003
Accession Number
ADA418261

Entities

People

  • Michael W. Weiner

Organizations

  • Northern California Institute for Research and Education

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anxiety Disorders
  • Brain
  • Classification
  • Data Analysis
  • Diseases And Disorders
  • Magnetic Resonance
  • Persian Gulf Syndrome
  • Questionnaires
  • Resonance
  • Signs And Symptoms
  • Spectroscopy
  • Traumatic Stress Disorder

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Medical Imaging.