Image-Guided Surgery of Primary Breast Cancer Using Ultrasound Phased Arrays
Abstract
Recent developments of piezocomposite transducer technology have lead to the development of new generation of ultrasound phased arrays with imaging and therapeutic capabilities. These dual-mode arrays provide an ideal nonionizing noninvasive tool for the treatment of primary breast cancer. This project investigates the thresholds for tissue damage under a variety of exposure conditions to high-intensity focused ultrasound from dual-mode arrays. In addition, we investigate new imaging techniques for enhanced visualization of thermal lesions in tissue media. These investigations are carried on ex-vivo animal tissue and in-vitro breast tissue and will lead to the design of a new generation of phased array drivers capable of supporting both the imaging and therapeutic requirements of the dual-mode system. During the second year of the grant, we have focused on the complete characterization of the imaging capabilities of the dual-mode array prototype for visualization of lesions in ex vivo tissue. We have also compared these imaging results with those obtained using a commercially available diagnostic scanner. The results validated the dual-more array approach and allowed us to finalize the design of the real-time data collection and beamforming algorithm. We are on track towards implementing a real-time dual-mode system suitable for in vivo animal experiments.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2003
- Accession Number
- ADA418748
Entities
People
- Emad S. Ebbini
Organizations
- University of Minnesota