Prostate Carcinoma Detection Using Combined Ultrasound, Elasticity, and Tissue Strain-Hardening Imaging
Abstract
The underlying hypothesis of this study is that remote, non-invasive measurements of elasticity in prostate glands are possible and can provide unique examiner-independent information that can increase the detection and/or characterization of potentially malignant masses in the prostate not accessible to manual palpation. The purpose of this study is to develop ultrasound technology to produce high-resolution displacement and strain data throughout the prostate for remote evaluation of the strain-dependent elastic (Young's or shear) modulus. To this end, the main objective of this research program is to test the hypothesis that quantitative elasticity images of the prostate can be obtained with real-time ultrasound. To achieve this objective, the authors have developed speckle tracking algorithms and methods for strain and elasticity imaging of the prostate. These studies include adaptive displacement and strain imaging, incompressibility processing, and strain-hardening imaging. Next, they will test the developed methods using tissue-mimicking and tissue-containing phantoms, and well-defined clinical studies. At the conclusion of the study, a prototype of the clinical prostate ultrasound elasticity imager will be designed. The overall program is intended to demonstrate that combined ultrasound, elasticity, and strain-hardening imaging permits surrogate, remote palpation of the prostate gland. (7 figures, 21 refs.)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2003
- Accession Number
- ADA419173
Entities
People
- Stanislav Y. Emelianov
Organizations
- University of Michigan