Novel Resuscitation from Lethal Hemorrhage-Suspended Animation for Delayed Resuscitation

Abstract

We have been working since the 1980s for the past 5 yrs under DOD support, on novel ways to resuscitate "unresuscitable" trauma victims. We focus on combat casualties who exsanguinate internally resulting within a few min in cardiac arrest (CA). We have conceived and documented the concept of "suspended animation (SA) for delayed resuscitation" using a hypothermic saline flush into the aorta within the first 5 min of CA, using novel clinically relevant outcome models in dogs. With the use of saline flush we have achieved complete recovery after circulatory arrests of up to 120 min at 10 degrees C. This is the report on yr 5. In yr 5, we developed strategies to make SA feasible for exsanguination CA victims.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2003
Accession Number
ADA419692

Entities

People

  • Peter Safar

Organizations

  • University of Pittsburgh

Tags

DTIC Thesaurus Topics

  • Cardiovascular Physiological Phenomena
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel

Fields of Study

  • Biology

Readers

  • Mathematics or Statistics
  • Trauma Surgery or Emergency Medicine.