Improving Blood Monitoring of Enzymes as Biomarkers of Risk Form Anticholinergic Pesticides and Chemical Warfare Agents

Abstract

Blood cholinesterase (ChE) biomarkers are an important way to monitor exposure to anticholinergic pesticides and chemical warfare (CW) agents and to establish whether some are at greater risk tan others form exposure to them. Many clinical and research laboratories use the colorimetric El lam assay based on the hydrolysis of acetylthiocholine. CHPPM (US Army Center For Health Promotion and Preventive Medicine) uses the Michel delta pH method to monitor more than 25,000 DoD personnel each year.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2003
Accession Number
ADA419695

Entities

People

  • Barry W. Wilson

Organizations

  • University of California

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acetylcholinesterases
  • Biological Markers
  • Blood
  • Blood Cells
  • California
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemistry
  • Clinical Laboratories
  • Conversion
  • Department Of Defense
  • Medical Personnel
  • Monitoring
  • Pesticides
  • Preventive Medicine
  • Regression Analysis
  • Warfare

Fields of Study

  • Agricultural and Food sciences

Readers

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  • Neurotoxicology
  • Research Science/Academic Research