Modifiable Risk Factors for Lymphedema in Breast Cancer Survivors

Abstract

Lymphedema of the arm is a common, yet dreaded consequence of breast cancer treatment that can result in substantial functional impairment and distress in affected women. Axillary surgery and radiation treatment are known risk factors for Lymphedema. However, other potentially modifiable characteristics or behaviors that may influence risk of this condition have not yet been studied. In this study, we will assess whether modifiable factors, including body weight, physical activity, smoking and breast reconstruction, influence risk of arm Lymphedema among women treated for breast cancer. Women aged 21-74 years diagnosed with a first primary invasive breast cancer will be identified through a population-based cancer registry. Enrollment will be limited to women who have had axillary node dissection, as the occurrence of Lymphedema is most common in these women. The incidence and timing of arm edema following breast cancer will be assessed using physical measures (arm volume) and self-report of symptoms, at regular intervals throughout the study. Each time they undergo arm measurement, women will complete questionnaires detailing and updating information on the exposures of interest and potential confounding factors. The study will be conducted over a 4-year period.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2003
Accession Number
ADA420077

Entities

People

  • Mary A. Rossing

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Body Weight
  • Breast Cancer
  • Breast Reconstruction
  • Cancer
  • Data Analysis
  • Data Management
  • Diseases And Disorders
  • Intervals
  • Lymphatic Diseases
  • Measurement
  • Neoplasms
  • Physical Activity
  • Questionnaires
  • Radiation
  • Risk Factors
  • Surgery

Fields of Study

  • Medicine

Readers

  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.